Η μέλισσα εμφανίστηκε 65.000.000 χρόνια πριν, κατά την τριτογενή περίοδο της καινοζωικής εποχής. Σε μη αλλεργικά άτομα, το τσίμπημά της ρυθμίζει τις ορμόνες του σώματος, ενεργοποιεί τη μνήμη και ελαττώνει τους πόνους των αρθρώσεων. Τα προϊόντα της μέλισσας, αποτέλεσαν στην αρχαία Ελλάδα αντικείμενα απόλαυσης, αλλά και έρευνας. Το μέλι αναφέρεται στην πρώτη ελληνική γραφή, την Γραμμική Β, ως MERL.
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